School of Biosecurity, Biotechnolgy and Laboratory Sciences (SBLS) Collection: Recent submissions
Now showing items 81-100 of 130
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Rapid detection and antibiotic resistance of Group B Streptococcus from women at Kawempe Hospital Kampala, Uganda
(Makerere University, 2022)An accurate and rapid bedside test undertaken in labour ward to detect Group B Streptococcus (GBS) maternal colonization has the potential to improve the effectiveness of intrapartum antibiotic prophylaxis prevention ... -
Second-line drug resistance markers as indicators of time to sputum culture conversion among selected mycobacterium tuberculosis clinical isolates at the Uganda National Tuberculosis Reference Laboratory
(2022)Drug-resistant TB continues to be a global public health crisis, with low treatment success rates for Multi Drug Resistant/ Rifampicin Resistant TB and Extensively Drug-Resistant TB. Achieving sustained bacteriological ... -
Antimicrobial resistance of staphylococcus aureus; knowledge, attitude, and practices on antibiotic use among farmers in Isingiro and Kamuli districts – Uganda
(Makerere University, 2022)Bacterial resistance to antibiotics is fast becoming a big challenge as resistance to multiple drugs is rising rapidly. The emergence of resistant Staphylococcus aureus worldwide is life-threatening for both the human and ... -
Seroprevalence and risk factors of Brucellosis in Camel and herdsmen in Benadir Region Somalia
(Makerere University, 2022)Camel brucellosis is a contagious disease that is often presented in a chronic condition caused by Brucella and affects both animals and pastoralists. The disease has been partially assessed in Somalia, especially since ... -
Antimicrobial profiles of E. coli, Salmonella and Campylobacter spp from raw and roasted chicken meat. A case of vending points along selected highways in Uganda
(Makerere University, 2022-03)Food-borne pathogens are an emerging threat in lieu of increased population growth and urbanization. Safety of ready-to-eat foods notably those on highways is questionable as several cases of gastro-intestinal issues have ... -
East Coast fever carrier status and Theileria parva breakthrough strains in recently ITM vaccinated cattle in Iganga District, Eastern Uganda
(Makerere University, 2022-04)East Coast fever (ECF), a tick-borne disease caused by Theileria parva (T. parva) is the most important hindrance to the livestock industry in the eastern, central and southern Africa which is the major source of income ... -
Frequency of Factor V-Leiden, Prothrombin G20210A, and Methylenetetrahydrofolate reductase mutations (c677t) among patients in Mulago sickle cell clinic
(Makerere University, 2022-04)Sickle cell diseases (SCD) is the major cause of death among children under 5 years. Some genetic polymorphisms associated with thrombophilia are known to increase the severity and frequency of this complication in sickle ... -
Spatio-temporal patterns of anthrax outbreaks in cattle in Kween and Arua Districts, Uganda
(Makerere University, 2022-02)A study was done to understand and compare the spatiotemporal patterns of cattle anthrax outbreaks with emphasis on progression, intensity, direction, and hotspot areas in Arua and Kween districts. Data were collected ... -
A comparative study of the efficiency and quality of six surfaces in drying Haplochromis SPP. (Nkejje) at Rubare Fish Landing Site in Lake Mburo protected area
(Makerere University, 2021-01)The study compared the efficiency and quality of the currently used traditional fish drying surface ‘Bare ground’ to five newly modified and improved surfaces in drying Haplochromis spp. (nkeje). The study was done at ... -
Diagnostic performance of four hepatitis B surface antigen CE marked and one WHO prequalified rapid diagnostic tests in Uganda
(Makerere University, 2022-02)Hepatitis B is a global health problem and as a blood-borne disease, it remains a common cause of viral hepatitis infection, with possible long-term complications of cirrhosis and hepatocellular carcinoma in patients who ... -
Prevalence of gastrointestinal parasites and molecular identification of benzimidazole resistance associated with beta-tubulin gene in adult Haemonchus contortus worms in goats from selected districts of Uganda
(Makerere University, 2022-01)Gastrointestinal parasites are among the most economically important pathogens of small ruminants causing serious economic losses and animal welfare problems for the livestock industry worldwide. Resistance against the ... -
Prevalence of leptospirosis among patients attending renal and general outpatient units in Mulago Hospital, Kampala, Uganda
(Makerere University, 2020-12)Leptospirosis is a zoonotic bacterial infection caused by spirochetes, which belong to the genus Leptospira. It is the most widespread zoonosis in the world and is considered a global public health threat. The dynamics of ... -
The validity of novel biomarkers in improving prediction and diagnosis of coronary heart disease : a case of Mengo Hospital
(Makerere University, 2020-08-25)Rising incidences of coronary heart disease is of great concern to public health especially among individuals without symptoms. This calls for accurate, early diagnosis which is the cornerstone for treatment, prognosis, ... -
Antibacterial activity and acute toxicity of herbs used in treatment of water borne diarrheal diseases in Butaleja District
(Makerere University, 2021-04)Uganda is still negatively impacted by a huge burden of water borne diseases, the heaviest being diarrhoeal diseases. This may result in high morbidity and mortality rates if left unattended to. The study documented herbs ... -
Assessment of human and veterinary drug shop sellers’ practices and awareness of antimicrobial resistance : a cross section study in Jinja, Uganda
(Makerere University, 2021-03)Antimicrobial resistance (AMR) is a global problem whereby it can affect any person regardless of age, sex, location among other factors. It occurs naturally, although the misuse of antibiotics in humans, animals and ... -
Assessing the performance of TB-HIV activities at Masaka Regional Referral Hospital, 2012-2014
(Makerere University, 2021-02)The TB-HIV co-infection burden globally, at regional level and locally, remains a health challenge that requires strong diagnosis, treatment and integrated support. A retrospective study was carried out at Masaka Regional ... -
Sero-prevalence of helicobacter pylori among patients with Gastro-Intestinal Tract (GIT) symptoms : a retrospective study at selected Africa Air Rescue (AAR) clinics in Kampala Area from 2015 - 2019
(Makerere University, 2021-02)Helicobacter pylori (HP) infection is extremely common worldwide, with almost half of the world’s population infected. In Uganda, no study has been done about the trends of sero-prevalence of H. pylori infection. Therefore, ... -
Determining the functionality of the putative twin-arginine signal peptides of rhomboid proteases from Mycobacterium tuberculosis using the beta-lactamase reporter system
(Makerere University, 2020)Rhomboid proteases are a group of integral membrane proteases present in several organisms. Because of their roles in many medically important processes, rhomboid proteases are potential drug targets. In Mycobacteria ... -
Bacterial pathogens associated with febrile conditions and their antimicrobial sensitivity pattern in children from Mbale hospital, Uganda
(Makerere University, 2021-02)Bacterial pathogens constitute a significant public health problem and are important cause of morbidity and mortality in febrile patients. The study was to determine the antimicrobial sensitivity pattern of bacterial ... -
Molecular characterization of transmitted/founder HIV-1 envelope Glycoproteins of Subtypes D and AD Recombinant viruses
(Makerere University, 2021-02)Infection by HIV-1 among heterosexuals most often results from successful transmission and propagation of a single virus variant, called Transmitted/Founder virus (TFV). This indicates that TFV have particular traits over ...