School of Biosecurity, Biotechnolgy and Laboratory Sciences (SBLS) Collection: Recent submissions
Now showing items 61-80 of 130
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Spatial and temporal distribution of foot and mouth disease in cattle in Uganda
(Makerere University, 2022-07-12)Background: Foot and Mouth disease is a notifiable transboundary disease, which is endemic in a large area of Sub-Saharan Africa, including Uganda. Recently, the disease has emerged from new areas, with a high impact, ... -
Climatic determinants of COVID-19 cases and deaths in Uganda: 2020-2022
(Makerere University, 2022-12-15)Introduction: Climate change has been shown to influence viral disease transmission. The strange fluctuations in cases and deaths due to COVID-19 could be due to the dynamics in weather patterns. This study aimed to explore ... -
Prevalence and associated risk factors of toxoplasmosis affecting pigs reared by small holder farmers in Wakiso and Mukono Districts of Central Uganda
(Makerere University, 2022-12)Porcine Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii. It leads to pig morbidity and mortality. It is transmitted by eating infected meat, touching surfaces or utensils contaminated by raw meat, ingestion ... -
The role of hyperferritinaemia in pediatric severe malaria pathogenesis and kidney injury
(Makerere University, 2023-01)Ferritin, a highly conserved iron storage protein that sequesters iron from pathogens including Plasmodium falciparum, is part of the acute phase response in malaria pathogenesis. Ferritin levels are elevated in severe ... -
Associations between plasmodium falciparum aminoquinoline resistance genotypes and clinical presentations of malaria in Ugandan children, A case control study of Jinja District and the neighbouring Busoga Sub-Region Districts
(Makerere University, 2023-01)Plasmodium falciparum resistance mutations to aminoquinoline antimalarials are selected by prior drug use and may alter parasite fitness yet their associations with clinical malaria presentations are uncertain. ... -
Investigation of viral respiratory co-infections and associated risk factors among SARS-COV-2 suspects in Uganda
(Makerere University, 2022-12-22)Respiratory coinfections are usually understudied during pandemics like the ongoing COVID-19 pandemic yet preceding outbreaks of respiratory infections like influenza have implicated coinfections as a major cause of ... -
Determination of Rubella virus strains associated with congenital birth defects in Uganda
(Makerere University, 2022-12-19)Rubella, a vaccine-preventable viral disease, is a highly contagious childhood disease caused by the rubella virus that is still prevalent in all regions except the Americas, where it has been eradicated. Rubella is a ... -
Antimicrobial knowledge among communities and sSusceptibility patterns of staphylococcus aureus isolated form wildlife-livestock-human Interface at Lake Mburo National Park, Western Uganda
(Makerere University, 2023-01-04)Antibiotic resistance has become a global public health concern because of the organisms causing infections are becoming resistant to most commonly prescribed antibiotic treatments, resulting in prolonged illness and greater ... -
Antimicrobial resistance profiles of Escerichia coli in different farming systems in Kamuli and Isingiro districts of Uganda
(Makerere University, 2022-12-16)Antimicrobial resistance (AMR) is a global crisis, as new forms of resistance emerge and are spreading quickly between continents. The problem of AMR is vast in developing countries, where the burden of infectious ... -
Prevalence of selected zoonotic gastrointestinal helminths and associated risk factors in free roaming domestic dogs in Kyegegwa District, Uganda
(Makerere University, 2022-12)Gastrointestinal helminths remain the most important parasitic infections affecting dogs worldwide and pose a risk to animal and human health. Helminth infections are most common in free roaming domestic dogs and stray ... -
Sero-prevalence and risk factors associated with Brucella Canis infection in dogs in Zombo District, Northwestern Uganda
(Makerere University, 2022)Canine brucellosis is an infectious debilitating disease of economic and public health significance in dogs worldwide. In Uganda, no systematic study has been conducted to establish the occurrence of the condition in dog ... -
Congenital plasmodium falciparum infection in a meso-endemic area of Uganda : molecular perspective
(Makerere University, 2022)Malaria remains a major public health concern especially among pregnant women and young children in sub-Saharan Africa. Few studies in Uganda have examined congenital malaria (CM) defined as presence of malaria parasites ... -
Sero prevalence and Brucella species circulating among small ruminants and their attendants in Kasese and Rubirizi Districts, South-Western Uganda
(Makerere University, 2022-09-05)In Uganda, brucellosis is more widely studied in cattle than in other species of animals. A few studies conducted on Brucellosis in small ruminants suggest that there exists a significant association between caprine, ovine ... -
Inflammatory marker profiles and seizure control in children with Nodding syndrome on antiepileptic drug therapy
(Makerere University, 2018-09)Background Nodding syndrome (NS) is a neurological disorder afflicting patients in Africa. The disease progresses from a prodromal stage to head nodding (its distinctive feature). Thereafter, convulsive seizures, worsening ... -
Lack of association between fluconazole susceptibility and ERG11 nucleotide polymorphisms in cryptococcus neoformans clinical isolates from Uganda
(Makerere University, 2022-08)Over 50% of Ugandan HIV-infected patients die due to cryptococcal meningitis [CM]-related complications. Fluconazole is the drug of choice for CM monoprophylaxis in resource-limited settings such as Uganda. Emerging ... -
Free-roaming domestic dog ecology: Population size and management in Soroti City
(Makerere University, 2022-08)Free-roaming dogs pose a public health threat. They are involved in the transmission of diseases to humans, livestock and wildlife. These dogs interact with many people, other dogs, and animals and are the most commonly ... -
Identification of potential antigenic peptides of Bm86, Ra85A and Ra92A tick proteins using insilico tools and immune dot blot assay
(Makerere University, 2022-04-28)Ticks are the leading causes of losses the livestock sector in sub-Saharan Africa through the spread of tick-borne infections. They are mostly controlled by chemical acaricides. The use of anti-tick vaccine to control ticks ... -
Evaluation of a sample pooling strategy for SARS-COV-2 by real time PCR
(Makerere University, 2022)Coronavirus disease 2019 (COVID-19) started as a cluster of pneumonia cases in Wuhan, China in December 2019 and became a global pandemic of international concern. Timely laboratory diagnosis of COVID-19 of all samples ... -
Effects of cytokine gene polymorphisms on il-10, tnf-α levels and oxidative stress in sickle cell disease patients from Mulago hospital, Uganda
(Makerere University, 2022-04-29)Sickle cell disease is a major cause of death in children under 5 years in Africa. Chronic oxidative stress and the release of inflammatory cytokines contribute to sickle cell disease pathogenesis and thus complicate the ... -
Ticks and tick-borne diseases of cattle in selected districts of Uganda : zoonotic potential and public health implications
(Makerere University, 2022)Background: According to the World Health Organization and other international health monitoring bodies, ticks have emerged as a major player in propagating human diseases, yet their involvement in zoonotic disease ...